Tottenham claimed a fourth successive Premier League win, as Erik Lamela's goal settled a 1-0 triumph at rivals West Ham.
Liverpool kept pace with Manchester City atop the Premier League thanks to Mohamed Salah's clever first-half finish.
A fractured arm has ruled the Argentine out of action for three weeks, meaning he sits out the Clasico and other key clashes for the Catalans
The Reds boss took Henderson's desire to stay on against Huddersfield Town as a good sign for his injury prospects.
The manager struggled to accept his side's 1-1 draw at home in Serie A action on Saturday
The defender and team-mate Ivan Rakitic both attempted to downplay fears of Barca faltering without their star man